SporeWeb

Bacillus Subtilis

Onset of sporulation – (Stage I - II)

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onset of sporulation


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Regulatory network interactions during the onset of sporulation

Active regulons during the onset of sporulation are indicated by green squares (proteins) or blue hexagons (sigma factors). Positive or negative effects on the transcription of genes (coloured circles) are indicated by connecting blue and red lines, respectively. In the case of Spo0A, a high-threshold effect is represented by thick lines and a low-threshold effect by thin lines. Important sporulation genes indicated as being part of the minimal sporulation set of genes  182 are indicated by thick black rims. Genes have been colour-coded according to their functional category (see legend in the grey vertical bar on the right). More information about specific genes can be accessed by clicking on the coloured circle.

 

 

 

 

Sporulation cycle of Bacillus subtilis

All genes have been colour-coded according to their functional category. Important germination genes that are part of the minimal sporulation set as determined by Galperin and coworkers 182 are indicated by thick black rims.

Class

    Antimicrobials
    Biofilm formation
    Cell division and DNA replication
    Cell wall degradation
    Cell wall metabolism
    Cell wall synthesis
    Competence
    DNA protection
    DNA repair
    Metabolism
    Mother cell lysis
    Mother cell metabolism
    Motility and chemotaxis
    Nucleotide biosynthesis
    Phosphorelay
    Resistance
    Respiration
    RNA chaperones
    Rnases
    Sortases
    Spore coat
    Spore coat assembly
    Spore coat maturation
    Spore cortex
    Spore germination
    Spore maturation
    Spore morphogenesis
    Sporulation protein
    Toxins and antitoxins
    Transcriptional regulation
    Translation
    Transport