Bacillus Subtilis

ScoC Pre-sporulation stage - the vegetative state of B. subtilis cells

lifecycleIII 50 vegetativestate 50 xlsx-3


ScoC in the vegetative state

ScoC (also known as Hpr or Cat) is a transition state regulator shown to be a sporulation inhibitor because of its repressing activity in the transcription of protease encoding genes during vegetative growth 12 and in oligopeptide uptake 11, 13. In addition, it inhibits the expression of the gene encoding the SinR antagonist SinI 14 and plays an important role in mediating catabolite repression 15. ScoC is produced during vegetative growth and has its expression enhanced by the presence of AbrB 16.


Sporulation cycle of Bacillus subtilis

1LocV 300