Bacillus Subtilis

SigE  Onset of sporulation – (Stage I - II)

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 Onset SigE png

SigE during the onset of sporulation

Under dual control of Spo0A~P and σA the spoIIG locus is transcribed 77, 79 consisting of spoIIGA, sigE (spoIIGB) and sigG (spoIIIG). σE is synthesized in an inactive state called pro-σE and requires both SpoIIGA and forespore-specific SpoIIR for activation 79, 80 (also see the COMMITMENT state). Pro-σE resides in the cytoplasmic membrane where it awaits proteolytic cleavage 81, 82.



Sporulation cycle of Bacillus subtilis

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